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[Issue No. 155] PSS E-Bulletin July 2019

Nomination closes on 15th Aug 2019 (Extended from 31st July 2019)

In this month’s issue, PSS Hospital Chapter interviews Mr Yeoh Siang Fei, a Senior Principal Clinical Pharmacist from National University Hospital. He is a well-respected critical care pharmacist with 14 years of experience in the adults’ intensive care unit (ICU) and 5 years in pediatrics’ ICU and today, he will be sharing his experience working in the field of critical care.

The Health Sciences Authority (HSA), in consultation with its Product Vigilance Advisory Committee, would like to update healthcare professionals on the outcome of its review regarding the risk of non-melanoma skin cancer (NMSC) associated with hydrochlorothiazide (HCTZ) use. Two recent Danish epidemiological studies had suggested a cumulative dose-dependent association between its use and NMSC. HSA's review concluded that while the Danish studies may not be fully applicable to the local context, there is biological plausibility of patients developing NMSC due to the photosensitizing effects of HCTZ. Hence, healthcare professionals are advised to consider the possible risk of NMSC in the use of HCTZ in their patients.